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Merck
CN

SML4066

Prolame

≥98% (HPLC)

Synonym(s):

(17β)-17-[(3-Hydroxypropyl)amino]estra-1,3,5(10)-trien-3-ol, N- (3-Hydroxy-1,3,5(10)-estratrien-17β-yl)-3-hydroxypropylamine

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About This Item

Empirical Formula (Hill Notation):
C21H31NO2
CAS Number:
Molecular Weight:
329.48
MDL number:
NACRES:
NA.21
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
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SMILES string

C[C@@]12[C@H](CC[C@@]1([H])[C@]3([H])CCC4=CC(O)=CC=C4[C@@]3([H])CC2)NCCCO

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear (Warmed)

storage temp.

2-8°C

Quality Level

Biochem/physiol Actions

Antithrombotic aminoestrogen.

Prolame is an antithrombotic aminoestrogen. Prolame has estrogenic effects similar to 17beta-estradiol (E2) but unlike E2, which has procoagulant effects, prolame is an antithrombotic and produces anticoagulant effects. It exhibits anxiolytic- and antidepressant-like effects in middle-aged female rats with less uterotrophic effects than 17β-estradiol.

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