SML4082
Paliperidone Palmitate
≥98% (HPLC)
Synonym(s):
3-(2-(4-(6-Fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-9-yl palmitate, 9-Hydroxyrisperidone palmitate, Hexadecanoic acid 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl ester, RO 92670
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About This Item
Quality Level
Assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
soluble (DMSO:TFA, 2 mg/mL, clear (add 1 drop TFA))
storage temp.
-10 to -25°C
SMILES string
Fc1cc2[o]nc(c2cc1)C3CCN(CC3)CCC4=C(NC5=C(CCCN5C4=O)OC(=O)CCCCCCCCCCCCCCC)C
InChI key
YOSKWMGLLZWACB-UHFFFAOYSA-N
Biochem/physiol Actions
Paliperidone palmitate is a long-acting injectable form of paliperidone, an atypical antipsychotic that targets dopamine D2 and serotonin 5-HT2A receptors to alleviate schizophrenia symptoms through neurotransmission regulation. Paliperidone palmitate also interacts with α1/α2 adrenergic and H1 histaminergic receptors, influencing both its therapeutic effects and side effect profile. The formulation′s sustained release mechanism promotes gradual absorption, ensuring stable drug levels for prolonged efficacy.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Oral
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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