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About This Item
Empirical Formula (Hill Notation):
C15H17N5O5
CAS Number:
Molecular Weight:
347.33
MDL number:
NACRES:
NA.21
SMILES string
O[C@@]1([C@@]([H])([C@]([H])(O[C@@]1([H])N2C=NC3=C2N=CN=C3NCC4=CC=CO4)CO)O)[H]
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
Quality Level
Biochem/physiol Actions
Naturally occurring purine nucleoside analog that protect cells against oxidative stress.
N6-Furfuryladenosine (Kinetin riboside) is a purine nucleoside analog. It is a naturally occurring plant cytokine and a product of oxidative DNA damage. N6-Furfuryladenosine protect cells against oxidative stress and delay of age-related phenotypes in human fibroblasts. N6-furfuryladenosine enhances mitochondrial turnover and bioenergetics in the diabetic mouse retina (Ins2Akita males). N6-Furfuryladenosine displays strong antiproliferative activity in various human cancer cells.
N6-Furfuryladenosine (Kinetin riboside) is a purine nucleoside analog. It is a naturally occurring plant cytokine and a product of oxidative DNA damage. N6-Furfuryladenosine protect cells against oxidative stress and delay of age-related phenotypes in human fibroblasts. N6-furfuryladenosine enhances mitochondrial turnover and bioenergetics in the diabetic mouse retina (Ins2Akita males). N6-Furfuryladenosine displays strong antiproliferative activity in various human cancer cells.
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Relaxation of mitochondrial hyperfusion in the diabetic retina via N6-furfuryladenosine confers neuroprotection regardless of glycaemic status
Anderson A, et al.
Nature Communications, 15 (2024)
Ewa Totoń et al.
Bioorganic & medicinal chemistry letters, 100, 129628-129628 (2024-01-28)
N6-[(Furan-2-yl)methyl]adenosine (kinetin riboside) and its seven synthesized analogues were examined for the ability to inhibit the growth of five human carcinoma cell lines and for comparison of normal human lung fibroblast cell line (MRC-5). Out of the compounds evaluated, 8-azakinetin
TaeKyung Nam et al.
Journal of microbiology and biotechnology, 33(9), 1206-1212 (2023-07-19)
Kinetin riboside is a naturally produced cytokinin that displays strong antiproliferative activity in various human cancer cells. However, the mechanism of chemoprevention in colorectal cancer cells has not been elucidated. We used a cell-based reporter system to identify kinetin riboside
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