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Merck
CN

SML4087

Spns2 inhibitor 16d

≥98% (HPLC)

Synonym(s):

3-(4-Decylphenyl)-1,2,4-oxadiazole-5-propanamine hydrochloride, SLF1081851

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About This Item

Empirical Formula (Hill Notation):
C21H33N3O·HCl
CAS Number:
Molecular Weight:
379.97
UNSPSC Code:
41106300
NACRES:
NA.21
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
Storage condition:
desiccated
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InChI

1S/C21H33N3O.ClH/c1-2-3-4-5-6-7-8-9-11-18-13-15-19(16-14-18)21-23-20(25-24-21)12-10-17-22;/h13-16H,2-12,17,22H2,1H3;1H

InChI key

ZJJXKBLUUGLWDW-UHFFFAOYSA-N

SMILES string

CCCCCCCCCCC1=CC=C(C=C1)C2=NOC(CCCN)=N2.Cl

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

Quality Level

Biochem/physiol Actions

Potent and selective inhibitor of Spns2 (spinster homolog 2) sphingosine-1-phosphate (SP1) transporter.
Spns2 inhibitor 16d (SLF1081851) is a potent and selective inhibitor of Spns2 (spinster homolog 2) sphingosine-1-phosphate (SP1) transporter. Spns2 inhibitor 16d (SLF1081851) decreases circulating plasma S1P and lymphocytes in mice and rats. Apparently, it locks Spns2 in the inward-facing state.

Disclaimer

Hygroscopic

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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