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Merck
CN
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About This Item

Empirical Formula (Hill Notation):
C10H8OS3
CAS Number:
Molecular Weight:
240.36
MDL number:
UNSPSC Code:
12352200
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Quality Level

Assay

≥98% (HPLC)

form

powder

color

, faint orange to red

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

S=C1SSC(C2=CC=C(C=C2)OC)=C1

Biochem/physiol Actions

Inhibitor of mitochondrial ROS production; medication used in the treatment of dry mouth.

Anethole Trithione (OP2113) is an old medication used in the treatment of dry mouth that increases salivary secretion and blocks carcinogenesis. It blocks mitochondrial ROS production. Anethole Trithione is a specific inhibitor of ROS production at the IQ site of complex I of the mitochondrial respiratory chain. It reduces pulmonary arterial pressure, remodeling, and hyperreactivity in CH-PH rats.

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