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About This Item
Empirical Formula (Hill Notation):
C19H29N5O2 · xHCl
CAS Number:
Molecular Weight:
359.47 (free base basis)
MDL number:
NACRES:
NA.28
SMILES string
O=C1N(C(CC(C1)(C)C)=O)CCCCN2CCN(C3=NC=CC=N3)CC2.[xHCl]
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
H2O: 2 mg/mL, clear
storage temp.
-10 to -25°C
Quality Level
Biochem/physiol Actions
Orally bioavailable, potent, and selective partial agonist of serotonin 5-HT1A receptor; non-sedative anxiolytic and antidepressant drug.
Gepirone hydrochloride is an orally bioavailable, non-sedative anxiolytic and antidepressant drug of the buspirone family with a unique mechanism of action that differs from other antidepressants and anxiolytic drugs. Gepirone acts as a partial serotonin 5-HT1A receptor agonist with differential action at pre-and postsynaptic 5-HT1A receptors. Gepirone is much more efficacious than selective serotonin reuptake inhibitors (SSRIs) without causing sexual dysfunction.
Gepirone hydrochloride is an orally bioavailable, non-sedative anxiolytic and antidepressant drug of the buspirone family with a unique mechanism of action that differs from other antidepressants and anxiolytic drugs. Gepirone acts as a partial serotonin 5-HT1A receptor agonist with differential action at pre-and postsynaptic 5-HT1A receptors. Gepirone is much more efficacious than selective serotonin reuptake inhibitors (SSRIs) without causing sexual dysfunction.
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