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SML4113

OGT2115

≥97% (HPLC)

Synonym(s):

2-[4-[[3-(4-Bromophenyl)-1-oxo-2-propen-1-yl]amino]-3-fluorophenyl]-5-benzoxazoleacetic acid, 2-[4-[[3-(4-Bromophenyl)-1-oxo-2-propenyl]amino]-3-fluorophenyl]-5-benzoxazoleacetic acid, OGT 2115, OGT-2115

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About This Item

Empirical Formula (Hill Notation):
C24H16BrFN2O4
CAS Number:
853929-59-6
Molecular Weight:
495.30
MDL number:
MFCD12828743
NACRES:
NA.28
Assay:
≥97% (HPLC)
Form:
powder
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Quality Segment

100

assay

≥97% (HPLC)

form

powder

color

white to beige

solubility

soluble (DMSO:0.1M NaOH (95:5), 1.0 mg/mL, clear, warmed, may need to sonicate.)

storage temp.

-10 to -25°C

Biochem/physiol Actions

Heparanase (HPSE) inhibitor with anti-angiogenesis potency and no inhibition of major human cytochrome P450 enzymes.

OGT 2115 is a heparanase (HPSE) inhibitor (IC50 = 0.4 μM) with anti-angiogenesis potency in human endothelial cell cultures (tubule formation IC50 = 1 μM) and no inhibition of major human cytochrome P450 enzymes (Cyp3A4 & Cyp2C9 IC50 > 30 μM).

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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