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Merck
CN

SML4119

Fisetin

≥95% (HPLC)

Synonym(s):

2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-4H-1-benzopyran-4-one, 3,3′,4′,7-Tetrahydroxyflavone; 5-Desoxyquercetin

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About This Item

Empirical Formula (Hill Notation):
C15H10O6
CAS Number:
Molecular Weight:
286.24
MDL number:
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Quality Level

Assay

≥95% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

room temp

SMILES string

OC1=CC=C2C(C(O)=C(OC2=C1)C3=CC(O)=C(C=C3)O)=O

Biochem/physiol Actions

Neuroprotective and antioxidant, slow cognitive decline in mice models of neurodegeneration.


Fisetin is a natural flavonoid found in various fruits and vegetables that exhibits neuroprotective and antioxidant activities. It inhibits PI 3-K, Akt, mTOR and Cdk6. Fisetin slow cognitive decline and the spread of pathology in mouse models of neurodegeneration.

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