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SML4146

Galidesivir Hydrochloride

≥95% (HPLC)

Synonym(s):

(2S,3S,4R,5R)-2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-(hydroxymethyl)pyrrolidine-3,4-diol hydrochloride, Immucillin A hydrochloride, BCX4430 hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C11H15N5O3 · xHCl
Molecular Weight:
265.27 (free base basis)
Assay:
≥95% (HPLC)
Form:
powder
Storage condition:
desiccated
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Quality Segment

100

assay

≥95% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

H2O: 2 mg/mL, clear

storage temp.

-10 to -25°C

Biochem/physiol Actions

Galidesivir (BCX4430) is an inhibitor of viral RNA-dependent RNA polymerase (RDRP) function with broad spectrum antiviral activity including against West Nile virus and tick-borne flaviviruses, Zika, haemorrhagic filoviruses Ebola and Marburg in addition to bunyaviruses, arenaviruses, paramyxoviruses, and coronaviruses. Galidesivir potently inhibits SARS-CoV-2 replication in cell-based assays. Also, it protected against Ebola virus and Marburg virus disease in rodent models and protected macaques from Marburg virus infection when given as late as 48 hours after infection.

Disclaimer

Hygroscopic Store with desiccant

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

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