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SML4169

Romifidine hydrochloride

Name: Romifidine hydrochloride
Brand: SIGMA

≥98% (HPLC), powder, α2-adrenergic receptor

Synonym(s):

2-(2-Bromo-6-fluoroanilino)-2-imidazoline hydrochloride, N-(2-Bromo-6-fluorophenyl)-4,5-dihydro-1H-imidazol-2-amine hydrochloride, STH 2130-Cl

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About This Item

Empirical Formula (Hill Notation):

C₉H₉BrFN_3.HCl

CAS Number:

65896-14-2

Molecular Weight:

294.55

MDL number:

MFCD16293882

NACRES:

NA.21

Assay:

≥98% (HPLC)

Form:

powder

Storage condition:

desiccated

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Properties

Quality Segment

100

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

H₂O: 2 mg/mL, clear

storage temp.

-10 to -25°C

SMILES string

FC1=CC=CC(Br)=C1NC2=NCCN2.Cl

Description

Application

Romifidine hydrochloride may be used to study its effects on sedation and pain management in animal models.

Biochem/physiol Actions

Romifidine is an α2-adrenergic receptor (α2-adrenoceptor) agonist with in vivo sedative and analgesic efficacy. Romifidine depresses excitatory postsynaptic potential in a neonatal rat hemisected spinal cord preparation ex vivo (high/low intensity e.p.s.p. EC50 = 23.4/22.0 µM), reversible by the selective α2-adrenoceptor antagonist atipamezole.

Disclaimer

Hygroscopic

pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c