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About This Item

Empirical Formula (Hill Notation):
C13H17NO4
CAS Number:
Molecular Weight:
251.28
UNSPSC Code:
12352200
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Quality Level

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

Biochem/physiol Actions

Metabolite present in human and mouse plasma that reduces food intake and body weight in diet-induced obese (DIO) mice.
BHB-Phe is a β-Hydroxybutyrate (BHB) secondary metabolite present in human and mouse plasma that exhibits anti-obesity activities. It reduces food intake and body weight in diet-induced obese (DIO) mice. Apparently BHB-Phe activates hypothalamic and brainstem neurons and suppresses feeding. BHB-Phe is synthesized in the body by catalytic condensation of BHB and Phenylalanine by CNDP2 (carnosine dipeptidase 2).

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