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SML4276

Plantamajoside

≥98% (HPLC)

Synonym(s):

2-(3,4-dihydroxyphenyl)ethyl 3-O -β-D-glucopyranosyl- β-D-glucopyranoside 4-[(2E )-3-(3,4-dihydroxyphenyl)-2-propenoate], PMS, Plantamoside, Purpureaside A

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About This Item

Empirical Formula (Hill Notation):
C29H36O16
CAS Number:
Molecular Weight:
640.59
MDL number:
NACRES:
NA.21
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

General description

Caffeic acid glycoside derivative that exhibits anti-inflammatory, antioxidative, antiapoptotic, antiaging, as well as antitumor activities.
Plantamajoside is a caffeic acid glycoside derivative that exhibits anti-inflammatory, antioxidative, antiapoptotic, antiaging, as well as antitumor activities. Plantamajoside suppresses the production of IL-1β, IL-6 and TNF-α in a dose-dependent manner, and inhibits phosphorylation of IκBα, p65, p38, JNK and ERK. Plantamajoside also inhibits LPS-induced PI3K and AKT phosphorylation and suppresses acute lung injury in mice. It protects hypoxia-reoxygenation-induced H9c2 cardiomyocytes injury by stimulating the ILK/c-Src/Akt signaling and inhibiting the mitochondrial apoptosis pathway.


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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable



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