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About This Item
Empirical Formula (Hill Notation):
C29H36O16
CAS Number:
Molecular Weight:
640.59
MDL number:
NACRES:
NA.21
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
General description
Caffeic acid glycoside derivative that exhibits anti-inflammatory, antioxidative, antiapoptotic, antiaging, as well as antitumor activities.
Plantamajoside is a caffeic acid glycoside derivative that exhibits anti-inflammatory, antioxidative, antiapoptotic, antiaging, as well as antitumor activities. Plantamajoside suppresses the production of IL-1β, IL-6 and TNF-α in a dose-dependent manner, and inhibits phosphorylation of IκBα, p65, p38, JNK and ERK. Plantamajoside also inhibits LPS-induced PI3K and AKT phosphorylation and suppresses acute lung injury in mice. It protects hypoxia-reoxygenation-induced H9c2 cardiomyocytes injury by stimulating the ILK/c-Src/Akt signaling and inhibiting the mitochondrial apoptosis pathway.
Plantamajoside is a caffeic acid glycoside derivative that exhibits anti-inflammatory, antioxidative, antiapoptotic, antiaging, as well as antitumor activities. Plantamajoside suppresses the production of IL-1β, IL-6 and TNF-α in a dose-dependent manner, and inhibits phosphorylation of IκBα, p65, p38, JNK and ERK. Plantamajoside also inhibits LPS-induced PI3K and AKT phosphorylation and suppresses acute lung injury in mice. It protects hypoxia-reoxygenation-induced H9c2 cardiomyocytes injury by stimulating the ILK/c-Src/Akt signaling and inhibiting the mitochondrial apoptosis pathway.
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Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
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