SML4305
Ceftiofur sodium salt
≥98% (HPLC)
Synonym(s):
(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(2-furanylcarbonyl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid monosodium salt, Sodium (6R,7R)-7-((Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-(((furan-2-carbonyl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, Ceftiofur sodium, U 64279E
Select a Size
About This Item
Quality Level
Assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
H2O: 2 mg/mL, clear (warmed)
storage temp.
2-8°C
General description
Ceftiofur sodium salt a third-generation β-lactam antibiotic, exhibits broad-spectrum bactericidal activity against many veterinary pathogens. Its core mechanism disrupts bacterial cell wall synthesis by irreversibly inactivating penicillin-binding proteins (PBPs) on the inner bacterial membrane, causing cell lysis. It shows potent activity with low MIC values against key pathogens like Pasteurella multocida (MIC90 ≤ 0.03 µg/ml) and Actinobacillus pleuropneumoniae (MIC90 ≤ 0.125 µg/ml). Parenterally administered due to poor oral absorption, ceftiofur rapidly metabolizes in vivo to desfuroylceftiofur (DFC), an equally active metabolite enhancing its efficacy. With a good therapeutic safety profile, ceftiofur is a significant veterinary antimicrobial for susceptible infections.
Disclaimer
Regulatory Information
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service