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SML4319

L-Azidonorleucine hydrochloride

≥98% (HPLC)

Synonym(s):

(S)-2-Amino-6-azidohexanoic acid hydrochloride, 6-Azido-L-norleucine hydrochloride, 6-Azido-L-lysine hydrochloride;, azidonorleucine HCl

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About This Item

Empirical Formula (Hill Notation):
C6H12N4O2 · xHCl
Molecular Weight:
172.19 (free base basis)
UNSPSC Code:
12352200
MDL number:
MFCD28387565
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
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Quality Segment

100

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

Biochem/physiol Actions

L-Azidonorleucine (ANL) is a noncanonical, slow to metabolize, and clickable amino acid that can be incorporated to proteins in cells that express a mutant methionyl-tRNA synthetase (MetRS). The newly synthesized MetRS-expressing cell-derived proteins from cell mixtures can then be enriched and examined in a cell-type-specific manner. The azido handle in ANL can be selectively conjugated to dyes and functionalized beads to enable visualization of proteins by FUNCAT (Fluorescence non-canonical amino acid tagging), and to purify proteins using BONCAT (bio-orthogonal non-canonical amino acid tagging).

Disclaimer

Hygroscopic Store with desiccant

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

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