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Merck
CN

SML4357

MIV-150

≥98% (HPLC)

Synonym(s):

MIV 150, PC 815, PC-815, N-(5-Cyano-2-pyridinyl)-N′-[(1S,2S)-2-[6-fluoro-2-hydroxy-3-(1-oxopropyl)phenyl]cyclopropyl]urea

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About This Item

Empirical Formula (Hill Notation):
C19H17FN4O3
CAS Number:
Molecular Weight:
368.36
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

Biochem/physiol Actions

MIV-150 is a nonnucleoside, highly potent allosteric inhibitor of HIV-1 and HIV-2 reverse transcriptase that is effective against multiple drug resistant HIV mutants including non-nucleoside reverse transcriptase inhibitors, nucleoside reverse transcriptase inhibitors, and protease inhibitors. It is under development as topical microbicide to prevent HIV infection.


Storage Class

11 - Combustible Solids

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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