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About This Item
Empirical Formula (Hill Notation):
C48H78O19
CAS Number:
Molecular Weight:
959.12
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
Biochem/physiol Actions
Asiaticoside, a blood-brain barrier (BBB) permeable pentacyclic triterpenoid glycoside, exhibits a diverse array of pharmacological activities, including neuroprotective, cardioprotective, hepatoprotective, and anti-inflammatory properties, among others. Asiaticoside demonstrates significant potential in cosmetic applications, particularly in anti-aging formulations, by promoting skin hydration, collagen synthesis, and UV protection. At the molecular level, asiaticoside exerts its effects through multiple mechanisms, including the inhibition of Aβ1-42 fibrillation and the modulation of various signaling pathways such as AMPK/Nrf2, TLR4/NF-κB/STAT3, and Wnt/β-catenin. Furthermore, asiaticoside′s therapeutic efficacy is attributed to its ability to regulate miRNA expression and influence key cellular processes through the modulation of cAMP/PKA, NOD2/MAPK/NF-κB, and JAK2/STAT3 signaling cascades.
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Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
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