Skip to Content
Merck
CN

SRP0357

NEK2 active human

recombinant, expressed in baculovirus infected Sf9 cells, ≥65% (SDS-PAGE)

Synonym(s):

HsPK21, NEK2A, NIMA (never in mitosis gene a)-related kinase 2, NLK1

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

NACRES:
NA.77
UNSPSC Code:
12352200
Form:
aqueous solution
Assay:
≥65% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in baculovirus infected Sf9 cells
Mol wt:
53 kDa
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


biological source

human

recombinant

expressed in baculovirus infected Sf9 cells

assay

≥65% (SDS-PAGE)

form

aqueous solution

mol wt

53 kDa

packaging

pkg of 10 μg

storage condition

avoid repeated freeze/thaw cycles

concentration

1.2 mg/mL

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... NEK2(4751)

General description

Human NEK2 (GenBank Accession No. NM_002497) full length with N-terminal HIS6-tag, MW=53 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Application

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Other Notes

One unit is defined as the amount of enzyme that will phosphorylate 1 nmol of myelin basic protein (MBP) substrate per minute at pH 7.4 and 30°C.


Still not finding the right product?

Explore all of our products under NEK2 active human


Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

新产品

This item has



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library



Lynda Fletcher et al.
Biochimica et biophysica acta, 1744(2), 89-92 (2005-06-14)
Two splice variants of Nek2 kinase, a member of the NIMA-related family, have been identified as Nek2A and Nek2B. Nek2A regulates centrosome disjunction, spindle formation checkpoint signaling, and faithful chromosome segregation. A specific role for Nek2B has not yet been
Margarida Fardilha et al.
Annals of the New York Academy of Sciences, 1030, 468-478 (2005-01-22)
Mammalian sperm were previously shown to express the PP1gamma2 isoform of protein phosphatase 1 (PP1) as well as its regulatory proteins inhibitor 2 and glycogen synthase kinase 3. Furthermore, the development of sperm motility during transit through the epididymis correlates



Global Trade Item Number

SKUGTIN
SRP0357-10UG04061832782188