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Merck
CN

SRP0365

Sigma-Aldrich

p70S6K active human

recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE)

Synonym(s):

PS6K, RPS6KB1, p70(S6K)-alpha, ribosomal protein S6 kinase, 70kDa, polypeptide 1

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.32
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biological source

human

recombinant

expressed in baculovirus infected Sf9 cells

Assay

≥70% (SDS-PAGE)

form

aqueous solution

mol wt

74 kDa

packaging

pkg of 20 μg

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... RPS6KB1(6198)

General description

Human p70S6K (GenBank Accession No. NM_003161), amino acid 1-421 with N-terminal GST tag, MW=74 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Application

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Salvatore Di Paolo et al.
American journal of kidney diseases : the official journal of the National Kidney Foundation, 49(3), 462-470 (2007-03-06)
The clinical challenge for the application of rapamycin and its derivatives as anticancer drugs is the ability to prospectively identify which tumors will be sensitive to mammalian target of rapamycin (mTOR) inhibition. The present study is designed to explore mTOR

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