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SRP0381

EZH2 /EED/SUZ12/RbAp48/AEBP2 human

recombinant, expressed in baculovirus infected Sf9 cells, ≥90% (SDS-PAGE)

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About This Item

NACRES:
NA.32
UNSPSC Code:
12352202
Biological source:
human
Recombinant:
expressed in baculovirus infected Sf9 cells
Assay:
≥90% (SDS-PAGE)
Form:
aqueous solution
Mol wt:
48 kDa (RbBP5), 51 kDa (EED), 53 kDa (AEBP2), 86 kDa (EZH2), 87 kDa (SUZ12)

Key Documents

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biological source

human

recombinant

expressed in baculovirus infected Sf9 cells

assay

≥90% (SDS-PAGE)

form

aqueous solution

mol wt

48 kDa (RbBP5), 51 kDa (EED), 53 kDa (AEBP2), 86 kDa (EZH2), 87 kDa (SUZ12)

packaging

pkg of 20 μg

NCBI accession no.

NM_003797 (EED), NM_004456 (EZH2), NM_005610 (RbAP48), NM_015355 (SUZ12), NM_153207 (AEBP2)

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... AEBP2(121536), EED(8726), EZH2(2146), RBBP4(5928), SUZ12(23512)

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General description

Mutant version of EZH2 5 member complex, with a Tyr- to-Ser mutation on amino acids 646 of the EZH2 protein (GenBank Accession No. NM_004456). This mutation is often cited in the scientific literature as Y641S in variant 3 (GenBank Accession No. NM_001203247).

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品
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Certificates of Analysis (COA)

Lot/Batch Number
5101310802

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Ryan D Morin et al.
Nature genetics, 42(2), 181-185 (2010-01-19)
Follicular lymphoma (FL) and the GCB subtype of diffuse large B-cell lymphoma (DLBCL) derive from germinal center B cells. Targeted resequencing studies have revealed mutations in various genes encoding proteins in the NF-kappaB pathway that contribute to the activated B-cell

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