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SRP0442

UEV1A active human

recombinant, expressed in E. coli, ≥80% (SDS-PAGE)

Synonym(s):

CIR1, CROC1, UBE2V1, ubiquitin-conjugating enzyme E2 variant 1

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About This Item

NACRES:
NA.32
UNSPSC Code:
12352202
Biological source:
human
Recombinant:
expressed in E. coli
Assay:
≥80% (SDS-PAGE)
Form:
aqueous solution
Mol wt:
20 kDa
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biological source

human

recombinant

expressed in E. coli

assay

≥80% (SDS-PAGE)

form

aqueous solution

mol wt

20 kDa

packaging

pkg of 100 μg

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... UBE2V1(7335)

General description

UEV1A (ubiquitin-conjugating enzyme E2 variant 1), also known as UBE2V1 or CROC-1 (GenBank Accession No. NM_021988) amino acids 2-170 (end) with N-terminal FLAG-tag, MW=20 kDa, expressed in E. coli.


Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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L Ma et al.
Oncogene, 17(10), 1321-1326 (1998-10-15)
Acquisition of the immortal phenotype by tumor cells represents an essential and potentially rate-limiting step in tumorigenesis. To identify changes in gene expression that are associated with the early stages of cell immortalization, we compared genetically matched pairs of pre-immortal
D Duong Hau et al.
Biochemistry, 45(32), 9866-9877 (2006-08-09)
Lys(63)-linked polyubiquitination of TRAF2 or TRAF6 is an essential step within the signal transduction cascade responsible for activation of p38, c-Jun N-terminal kinase, and the transcription factor NF-kappaB. Attachment of ubiquitin (Ub) to a TRAF, and conjugation of Ub molecules
T M Thomson et al.
FEBS letters, 423(1), 49-52 (1998-05-15)
The open reading frame YGL087c in the budding yeast Saccharomyces cerevisiae genome encodes a polypeptide highly similar to the human UEV (ubiquitin-conjugating E2 enzyme variant) proteins, which have been proposed to belong to a family of putative dominant negative ubiquitin



Global Trade Item Number

SKUGTIN
SRP0442-100UG04061832782522