SRP2077
p53 (1-363) C-terminal deletion human
recombinant, expressed in insect cells, ≥80% (SDS-PAGE)
别名:
FLJ92943, LFS1, P53, TRP53
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关于此项目
NACRES:
NA.26
UNSPSC Code:
12352200
Form:
frozen liquid
Assay:
≥80% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in insect cells
Mol wt:
~41.8 kDa
biological source
human
recombinant
expressed in insect cells
assay
≥80% (SDS-PAGE)
form
frozen liquid
mol wt
~41.8 kDa
packaging
pkg of 5 μg
concentration
850 μg/mL
color
clear colorless
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... TP53(7157)
Biochem/physiol Actions
Human p53 protein is composed of 393 amino acid residues with several distinct regions. The N-terminal activation domain allows p53 protein to recruit the basal transcription machinery and activate the expression of target genes, whereas the core domain binds to target DNA in a sequence-specific manner and the majority of mutations found in human tumors occur in the region of the gene encoding this domain. The C-terminal domain is composed of predominantly basic residues and modification of the C-terminal basic domain, including acetylation, glycosylation and phosphorylation, is an essential mechanism for regulating p53 function.
Physical form
Clear and colorless frozen liquid solution
Preparation Note
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable