SRP2104
Arginine Splicing Factor, His tagged human
recombinant, expressed in insect cells, ≥85% (SDS-PAGE)
Synonym(s):
ASF, FLJ53078, MGC5228, SF2, SF2p33, SFRS1, SRp30a
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About This Item
NACRES:
NA.26
UNSPSC Code:
12352202
biological source
human
recombinant
expressed in insect cells
assay
≥85% (SDS-PAGE)
form
frozen liquid
mol wt
~29.3 kDa
packaging
pkg of 5 μg
storage condition
avoid repeated freeze/thaw cycles
concentration
350 μg/mL
color
clear, colorless
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... SRSF1(6426)
Biochem/physiol Actions
ASF also known as SF2 is a member of the SR protein family. It is an essential pre-mRNA splicing factor required for both single and alternative splicing. Phosphorylation on serine residues located within the SR domain directly regulates ASF/SF2 activity and compartmentalization of other SR splicing factors. In addition to interacting with RNA and other splicing factors, such as U1-70K, U2AF and other SR proteins, ASF/SF2 also directly or indirectly interacts with HIV regulatory protein Rev, the C-terminal domain (CTD) of the largest subunit of RNA polymerase II, and numerous transcription factors, thereby suggesting a potential role of ASF/SF2 in coordinating transcription and pre-mRNA splicing.
Physical form
Clear and colorless frozen liquid solution
Preparation Note
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.
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Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| SRP2104-5UG | 04061837201066 |