SRP4053
FGF-8 human
recombinant, expressed in E. coli, ≥95% (SDS-PAGE)
Synonym(s):
AIGF, FGF-8b, FGF8, Fibroblast Growth Factor-8, HBGF
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About This Item
biological source
human
recombinant
expressed in E. coli
assay
≥95% (SDS-PAGE)
form
lyophilized
potency
≥2x10^6 units/mg
mol wt
~22.4 kDa
packaging
pkg of 25 μg
storage condition
avoid repeated freeze/thaw cycles
impurities
endotoxin, tested
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... FGF8(2253)
General description
Fibroblast growth factor-8 (FGF-8) is also known as androgen-induced growth factor (AIGF). It is a heparin-binding growth factor. The gene encoding this protein is localized on human chromosome 10. Recombinant human FGF-8 is a 22.4kDa protein containing 193 amino acid residues.
Biochem/physiol Actions
Fibroblast growth factor-8 (FGF-8) stimulates the proliferation and activation of cells that express the FGF receptors. It has a role in embryogenesis. FGF8b, an isoform of FGF-8, is expressed in prostate cancer.
Physical form
Lyophilized in 10 mM Tris, pH 8.0 plus 75 mM NaCl. The protein may appear as a haze or film, which may not be seen at the bottom of the vial.
Preparation Note
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitute in 5 mM Tris, pH 8.0 to a concentration of 0.1-1 mg/mL. This solution can be diluted into other aqueous buffers.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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