SRP4134
IL-3 human
recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
Synonym(s):
HCGF, IL-3, Interleukin-3, MCGF (Mast cell growth factor), MGC79398, Multi-CSF, P-cell stimulation factor
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About This Item
General description
IL-3 is a species-specific colony-stimulating factor that stimulates colony formation of megakaryocytes, neutrophils, and macrophages from bone marrow cultures. Recombinant human IL-3 is a 15.0 kDa protein containing 133 amino acid residues.
Biochem/physiol Actions
Interleukin-3 (IL-3) is a hematopoietic growth factor. The gene encoding it is localized on human chromosome 5. It has a role in cell proliferation and activates different signaling cascades. It is crucial for the differentiation of hematopoietic-derived endothelial progenitor cells (EPCs). The differentiation of erythroid cells, mast cells and granulocytes is stimulated by IL-3. The protein has been linked to schizophrenia.
Physical form
Lyophilized without additives.
Preparation Note
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitute in water to a concentration of 0.1-1.0 mg/mL. The solution can then be diluted into other aqueous buffers.
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Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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