SRP4210
GRO/KC from mouse
recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
Synonym(s):
CXCL1, GRO α, GRO1, Growth-regulated α protein, NAP-3
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About This Item
biological source
mouse
recombinant
expressed in E. coli
assay
≥98% (HPLC), ≥98% (SDS-PAGE)
form
lyophilized
potency
10-100 ng/mL
mol wt
~7.8 kDa
packaging
pkg of 20 μg
impurities
endotoxin, tested
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
mouse ... Cxcl1(14825)
General description
Growth-regulated oncogenes (GRO)/keratinocyte chemoattractant (KC) belongs to the growing inflammatory protein superfamily. KC is characterized with four conserved cysteine residues with a CXC motif.
Mouse KC (also known as mouse GRO-α) belongs to the C-X-C family of chemokines. Mouse KC is a 7.8 kDa protein containing 72 amino acid residues.
Biochem/physiol Actions
Growth-regulated oncogenes (GRO)/keratinocyte chemoattractant (KC) plays a vital role in wound healing and inflammation. In rat, serum levels of GRO/KC can be used as a predictive biomarker for inhibitory effect of chemopreventive agents on esophageal carcinogenesis.
Physical form
Sterile filtered and then lyophilized without any additives.
Preparation Note
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitute in water to a concentration of 0.1-1 mg/mL. This solution can be diluted into other aqueous buffers.
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