SRP4388
SDF-1alpha (CXCL12) from mouse
recombinant, expressed in E. coli, ≥99% (SDS-PAGE), ≥99% (HPLC)
Synonym(s):
CXCL12, PBSF, Pre-B cell growth-stimulating factor, SDF-1, chemokine (C-X-C motif) ligand 12, hIRH
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About This Item
biological source
mouse
recombinant
expressed in E. coli
assay
≥99% (HPLC), ≥99% (SDS-PAGE)
form
lyophilized
potency
50-100 ng/mL
mol wt
~7.9 kDa
packaging
pkg of 10 μg
storage condition
avoid repeated freeze/thaw cycles
impurities
endotoxin, tested
NCBI accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
mouse ... Sdf1(20315)
General description
Stromal Cell-Derived Factor-1α (SDF-1α) is a recently discovered protein belonging to the α-chemokine (C-X-C) family of cytokines. Recombinant mouse SDF-1α is a 7.9kDa protein containing 68 amino acids residues.
Biochem/physiol Actions
Stromal Cell-Derived Factor-1α (SDF-1α) is a pleiotropic chemokine. It works as a chemoattractant for T- and B-lymphocytes and inflammatory monocytes. In neural stem cells, SDF-1α is needed for proliferation, survival, migration, intercellular interaction and guidance to neuronal axon. It is responsible for pathogenic inflammation in the central nervous system (CNS). It also controls BMP (bone morphogenic protein)-associated osteogenic differentiation.
Physical form
Lyophilized from 10 mM acetic acid. The protein may appear as a haze or film, which is difficult to see at the bottom of the vial.
Preparation Note
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitution in water to a concentration of 0.1-1.0 mg/mL. The solution can then be diluted into other aqueous buffers.
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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