SRP5164
BAD, GST tagged human
recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
Synonym(s):
BBC2, BCL2L8
Physical form
Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Preparation Note
after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Autoimmune Type 1 Diabetes
Diabetes (2016)
BAD overexpression inhibits cell growth and induces apoptosis via mitochondrial-dependent pathway in non-small cell lung cancer
Li Jiang
Cancer Cell International (2013)
Romaine Fernando et al.
The Journal of biological chemistry, 282(39), 28864-28873 (2007-08-03)
Recent investigations suggest that functions of the proapoptotic BCL2 family members, including BAD, are not limited to regulation of apoptosis. Here we demonstrate that BAD inhibits G(1) to S phase transition in MCF7 breast cancer cells independent of apoptosis. BAD
The role of Bcl-2 and its pro-survival relatives in tumourigenesis and cancer therapy
PN Kelly
Cell Death and Differentiation (2011)
Overexpression of Bcl-2?Associated Death Inhibits A549 Cell Growth In Vitro and In Vivo
Na Huang
Cancer biotherapy & radiopharmaceuticals (2012)
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