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Merck
CN

SRP6318

Kininogen,HMW from human plasma

≥95% (SDS-PAGE)

Synonym(s):

Alpha-2-thiol proteinase inhibitor, BDK, Fitzgerald factor, High molecular weight Kininogen, KNG, Kininogen-1 heavy chain, Kininogen-1 light chain, Low molecular weight growth-promoting, Lysyl-bradykinin, T-kinin Bradykinin, Williams-Fitzgerald-Flaujeac factor

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About This Item

NACRES:
NA.32
UNSPSC Code:
12352200
Biological source:
human plasma
Assay:
≥95% (SDS-PAGE)
Form:
frozen liquid
Mol wt:
120 kDa

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biological source

human plasma

assay

≥95% (SDS-PAGE)

form

frozen liquid

mol wt

120 kDa

packaging

pkg of 100 μg

UniProt accession no.

P01042

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... KNG1(3827)

General description

HMW kininogen, synthesized by hepatocytes, is a multifunctional protein. It is the precursor protein of bradykinin. In addition it is a cofactor in the activation of factor XI, XII, and prekallikrein and a major extra-cellular cysteine proteinase inhibitor. Kininogens inhibit systemic proteases which are thought to have a part in various diseases such as cancer, muscular dystrophy and joint disease.

Physical form

Frozen in 10 mM Na acetate, pH 5.5 with 250 mM NaCI.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品
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Certificates of Analysis (COA)

Lot/Batch Number
5G23L3000

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