SRP6553
CIRBP/Cold-inducible RNA-binding protein human
recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
Synonym(s):
A18HNRNP, CIRP
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About This Item
NACRES:
NA.32
UNSPSC Code:
12352202
Form:
lyophilized
Assay:
≥90% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in E. coli
Mol wt:
20.5 kDa
biological source
human
recombinant
expressed in E. coli
assay
≥90% (SDS-PAGE)
form
lyophilized
mol wt
20.5 kDa
packaging
pkg of 1 mg, pkg of 20 μg
impurities
≤1 EU/μg endotoxin (LAL test)
UniProt accession no.
shipped in
wet ice
storage temp.
−70°C
Gene Information
human ... CIRBP(1153)
General description
CIRBP, also known as cold-inducible RNA-binding protein, plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP responds to a wide array of cellular stresses, including short wavelength ultraviolet light (UVC), at the transcriptional and post-translational level. It acts as a translational activator. CIRBP can bind the 3′untranslated region of specific transcripts to stabilize them and facilitate their transport to ribosomes for translation. CIRBP affects NF-κB signaling as opposed to IL1B mRNA stability directly.
Physical form
Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 0.25 M Imidazole, 20% glycerol.
Preparation Note
Detailed reconstitution instructions are sent along with the product
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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