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Merck
CN

SRP8008

FTO mouse

recombinant, expressed in E. coli, His tagged, >90% (SDS-PAGE)

Synonym(s):

EC 1.14.11, FATSO, Fat mass and obesity-associated protein, Preadipocyte factor 1

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About This Item

NACRES:
NA.32
UNSPSC Code:
12352200
Assay:
>90% (SDS-PAGE)
Biological source:
mouse
Recombinant:
expressed in E. coli
Concentration:
≥0.2 mg/mL
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biological source

mouse

recombinant

expressed in E. coli

tag

His tagged

assay

>90% (SDS-PAGE)

form

liquid

mol wt

~55 kDa by SDS-PAGE

packaging

pkg of 10 μg

storage condition

avoid repeated freeze/thaw cycles

concentration

≥0.2 mg/mL

impurities

<1 EU/μg endotoxin, tested

color

clear

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

mouse ... Fto(26383)

General description

FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ′fused toes′ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.

Physical form

Solution in 55 mM TRIS-HCl, pH 8.2, containing 150 mM NaCl.

Other Notes

Mouse FTO (aa 2-502) is fused at the N-terminus to a His-tag.


Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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