SRP8032
IL-1 Receptor Type I (human): FC (human)
recombinant, expressed in HEK 293 cells, >95% (SDS-PAGE)
Synonym(s):
Interleukin-1 receptor alpha, Interleukin-1 receptor type I, RI, Serpin F1
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About This Item
UNSPSC Code:
12352200
NACRES:
NA.32
biological source
human
recombinant
expressed in HEK 293 cells
Assay
>95% (SDS-PAGE)
form
lyophilized
mol wt
~80 kDa by SDS-PAGE
packaging
pkg of 50 μg
storage condition
avoid repeated freeze/thaw cycles
impurities
<0.1 EU/μg endotoxin, tested
color
white
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... IL1R1(3554)
General description
IL-1RI is the receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappaB. Signaling involves formation of a ternary complex containing IL1RAP, leading the activation of TOLLIP, MYD88, and IRAK1 or IRAK2.
Physical form
Lyophilized from PBS.
Preparation Note
Reconstitute with 50 μL deionized water.
Other Notes
Human IL-1RI (interleukin-1 receptor type I) (aa 21-336) is fused at the C-terminus to the Fc portion of human IgG1.
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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