SRP8038
IL-38 mouse
>95% (SDS-PAGE), recombinant, expressed in E. coli, FLAG® tagged, lyophilized
Synonym(s):
CD223, Interleukin-1 family member 10, Interleukin-38
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About This Item
UNSPSC Code:
12352202
NACRES:
NA.32
Product Name
IL-38 mouse, recombinant, expressed in E. coli, FLAG® tagged, >95% (SDS-PAGE)
biological source
mouse
recombinant
expressed in E. coli
tag
FLAG® tagged
assay
>95% (SDS-PAGE)
form
lyophilized
mol wt
~20 kDa
packaging
pkg of 10 μg
storage condition
avoid repeated freeze/thaw cycles
impurities
<0.01 EU/μg endotoxin, tested
color
white
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
mouse ... Il1f10(215274)
Legal Information
FLAG is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
IL-38 [IL-1F10] (mouse) (aa 3-152) is fused at the C-terminus to a FLAG-tag.
Physical form
Lyophilized from PBS and 0.5% trehalose.
General description
IL-38 (IL-1F10) mRNA is expressed in heart, placenta, fetal liver, spleen, thymus and tonsil. The expression in a variety of immune tissues and similarity to IL-1Ra suggest a role of IL-1F10 in the inflammatory response.
Preparation Note
Reconstitute with 100 μL deionized water.
Storage Class
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Ina Rudloff et al.
Arthritis & rheumatology (Hoboken, N.J.), 67(12), 3219-3225 (2015-09-01)
Knowledge of interleukin-38 (IL-38), formerly IL-1 family member 10, is sparse, but Il1f10 polymorphisms are associated with inflammatory diseases, and recombinant IL-38 inhibits inflammatory responses similar to those reported in the context of systemic lupus erythematosus (SLE). We undertook this
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