SRP8048
PEDF mouse
recombinant, expressed in CHO cells, FLAG® tagged, >95% (SDS-PAGE)
Synonym(s):
Caspin, PC cell-derived growth factor, Pigment epithelium-derived factor, Stromal cell-derived factor 3
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About This Item
Form:
lyophilized
Assay:
>95% (SDS-PAGE)
Biological source:
mouse
Recombinant:
expressed in CHO cells
Mol wt:
~47 kDa by SDS-PAGE
biological source
mouse
recombinant
expressed in CHO cells
tag
FLAG® tagged
assay
>95% (SDS-PAGE)
form
lyophilized
mol wt
~47 kDa by SDS-PAGE
packaging
pkg of 10 μg
storage condition
avoid repeated freeze/thaw cycles
impurities
<0.01 EU/μg endotoxin, tested
color
white
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
mouse ... Serpinf1(20317)
General description
Pigment epithelium-derived factor (PEDF) is a 47kDa secreted glycoprotein that belongs to the non-inhibitory serpin family group. PEDF is widely expressed in adult and fetal tissues, including brain, spinal cord, plasma, bone, prostate, pancreas, heart and lung. PEDF acts as an angiogenesis inhibitor with neurotrophic, immunomodulation and antitumor properties. It functions as anti-angiogenic agent by counterbalancing the proangiogenic effect of VEGF. PEDF is one of the most abundant proteins released by adipocytes and induces insulin resistance in adipocytes and human skeletal muscle cells. Recently, it has been reported that PEDF is sufficient to maintain the self-renewal of pluripotent human embryonic stem cells.
Physical form
Lyophilized from PBS.
Preparation Note
Reconstitute with 100 μL deionized water.
Other Notes
Mouse PEDF (aa 20-417) is fused at the C-terminus to a FLAG®-tag.
Legal Information
FLAG is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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