Tenoxicam

Name: Tenoxicam
Brand: SIGMA

NSAID

Synonym(s):

4-Hydroxy-2-methyl-N-2-pyridinyl-2H-thieno(2,3-e)-1,2-thiazine-3-carboxamide 1,1-dioxide

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About This Item

Empirical Formula (Hill Notation):

C₁₃H₁₁N₃O₄S₂

CAS Number:

59804-37-4

Molecular Weight:

337.37

NACRES:

NA.77

PubChem Substance ID:

24899922

UNSPSC Code:

12352202

MDL number:

MFCD00083502

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Properties

Quality Segment

100

assay

≥98% (perchloric acid titration)

form

powder

solubility

DMF: 25 mg/mL, clear, yellow-green

SMILES string

O=C(NC1=NC=CC=C1)C2=C(O)C(SC=C3)=C3S(N2C)(=O)=O

InChI

1S/C13H11N3O4S2/c1-16-10(13(18)15-9-4-2-3-6-14-9)11(17)12-8(5-7-21-12)22(16,19)20/h2-7,17H,1H3,(H,14,15,18)

InChI key

LZNWYQJJBLGYLT-UHFFFAOYSA-N

Description

Application

Tenoxicam has been used:

as a non-steroidal anti-inflammatory agent (NSAID) to study its effects on root gravitropism in Arabidopsis thaliana
as a standard in microanalysis of NSAIDs by spectrophotometry
to test its effect on surface potential andmembrane fluidity modification in phosphoglyceride monolayers

Biochem/physiol Actions

Non-steroidal antiinflammatory drug (NSAID) with comparatively low risk of renal or hepatic toxicity.

Tenoxicam (TX) possesses antipyretic and analgesic effects. It elicits radical scavenging activity and has the potential to treat enkylosing spondylitis, extra-articular diseases, acute gout, and rheumatic diseases. It is also effective in treating primary dysmenorrhea, postpartum uterine contraction pain, and post-operation backaches. TX is capable of inhibiting prostaglandin synthesis.