T111040
DMT-dT Phosphoramidite
configured for MerMade
Synonym(s):
5′-O-(4,4′-dimethoxytrityl)-2′-deoxythymidine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite], 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxythymidine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite], DMT-dT amidite, Thymidine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
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About This Item
biological source
non-animal source (no BSE/TSE risk)
Quality Level
type
for DNA synthesis
product line
Proligo Reagents
assay
≥99% (31P-NMR), ≥99.0% (reversed phase HPLC)
form
powder or granules
technique(s)
oligo synthesis: suitable
impurities
≤0.3 wt. % water content (Karl Fischer)
color
white to off-white
solubility
water: 0.00051 g/L at 20 °C
λ
conforms (UV/VIS Identity)
compatibility
configured for MerMade
nucleoside profile
base: deoxythymidine
base protecting group: none
2' protecting group: none
5' protecting group: DMT
deprotection: fast/standard
storage temp.
2-8°C
SMILES string
COc1ccc(cc1)C(OC[C@H]2O[C@H](C[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)N3C=C(C)C(=O)NC3=O)(c4ccccc4)c5ccc(OC)cc5
InChI
1S/C40H49N4O8P/c1-27(2)44(28(3)4)53(50-23-11-22-41)52-35-24-37(43-25-29(5)38(45)42-39(43)46)51-36(35)26-49-40(30-12-9-8-10-13-30,31-14-18-33(47-6)19-15-31)32-16-20-34(48-7)21-17-32/h8-10,12-21,25,27-28,35-37H,11,23-24,26H2,1-7H3,(H,42,45,46)/t35-,36+,37+,53?/m0/s1
InChI key
UNOTXUFIWPRZJX-CEXSRUIHSA-N
General description
- Exocyclic amine functions are protected by a benzoyl group (dA(bz) and dC(bz)) or isobutyryl group (dG(ib))
- Recommended cleavage and deprotection conditions are 8 hours at 55 °C or 24 hours at room temperature using concentrated ammonia solution for standard base-protected oligonucleotides
- The high coupling efficiency of Proligo′s DNA phosphoramidites leads to high-yield and high-quality oligonucleotides (a)
Packaging
T111040-10G packaged in a 8 oz bottle with a 28-400 cap
T111040-6x5G packaged in a 8 oz bottle with a 28-400 cap
T111040-6x10G packaged in a 8 oz bottle with a 28-400 cap
T111040-20x10G packaged in a 1 L bottle with GL 45
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Storage Class
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| T111040-6X8.20G | 04061838688316 |
| T111040-10G | 04061832949765 |
| T111040-6X16.8G | 04061832949796 |
| T111040-20X10G | 04061832949772 |
| T111040-6X10G | 04061832949789 |
| T111040-1G | 04061826658642 |
| T111040-6X5G | 04061832949802 |