T1126
Thyroglobulin from porcine thyroid gland
powder
Synonym(s):
TG human
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About This Item
Form:
powder
Biological source:
Porcine thyroid
Mol wt:
~670 kDa
biological source
Porcine thyroid
Quality Level
form
powder
mol wt
~670 kDa
composition
Iodine, ≥0.3%
nitrogen analysis
14.0-17.5% total
technique(s)
protein purification: suitable
ash
≤4%
pI
4.58
UniProt accession no.
storage temp.
−20°C
Gene Information
pig ... TG(100156471)
Biochem/physiol Actions
Thyroglobulin has been shown to regulate the transcription of iodide porters including sodium iodide symporter and pendrin.
Thyroglobulin is a major protein involved with iodine metabolism. It consists of an iodine-containing protein that is stored in the thyroid gland and is converted into circulating thyroxines when the thyroid is stimulated by TSH (Thyroid Stimulating Hormone) from the pituitary. Thyroglobulin is often used as a carrier protein for the production of antibodies. Its advantage as a carrier protein comes from its large number of tyrosine residues that can be used for conjugation using the diazo reaction.
Preparation Note
When reconstituted in water (20 mg/ml), a turbid solution with some insolubles is observed.
Other Notes
Electrophoretically heterogeneous.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
涉药品监管产品
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Sanathana Konugolu Venkata Sekar et al.
Scientific reports, 8(1), 10015-10015 (2018-07-04)
Thyroid plays an important role in the endocrine system of the human body. Its characterization by diffuse optics can open new path ways in the non-invasive diagnosis of thyroid pathologies. Yet, the absorption spectra of tyrosine and thyroglobulin-key tissue constituents
Effects of Selenium Supplement on B Lymphocyte Activity in Experimental Autoimmune Thyroiditis Rats.
Yang Li et al.
International journal of endocrinology, 2021, 9439344-9439344 (2021-08-24)
45 healthy and adult female SD rats were randomly divided into three groups: normal control group, EAT model group, and selenium yeast supplement EAT group. The EAT model rats were induced by subcutaneous injection of porcine thyroglobulin and fed with
Tanuza Nazmul et al.
Microbiology and immunology, 67(7), 334-344 (2023-05-30)
We first investigated the interactions between several algae-derived lectins and severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). We created lectin columns using high-mannose (HM)-type glycan-specific lectins OAA and KAA-1 or core fucose-specific lectin hypninA-2 and conducted binding experiments with SARS-CoV-2. The
Global Trade Item Number
| SKU | GTIN |
|---|---|
| T1126-500MG | 04061833493496 |
| T1126-100MG | 04061833435281 |
| T1126-1G | 04061826658659 |