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T1512

Tetramisole hydrochloride

Name: Tetramisole hydrochloride
Brand: SIGMA

powder, ≥99% (TLC)

Synonym(s):

(±)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole hydrochloride

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About This Item

Empirical Formula (Hill Notation):

C₁₁H₁₂N₂S · HCl

CAS Number:

5086-74-8

Molecular Weight:

240.75

NACRES:

NA.77

PubChem Substance ID:

24278725

UNSPSC Code:

12352202

EC Number:

225-799-5

MDL number:

MFCD00005536

Beilstein/REAXYS Number:

4358989

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Properties

Product Name

Tetramisole hydrochloride, phosphatase inhibitor

biological source

synthetic (organic)

Quality Segment

200

description

alkaline phosphatase inhibitor

assay

≥99% (TLC)

form

powder

mp

266-267 °C (lit.)

solubility

water: 50 mg/mL, clear, colorless

SMILES string

Cl[H].C1CN2CC(N=C2S1)c3ccccc3

InChI

1S/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H

InChI key

LAZPBGZRMVRFKY-UHFFFAOYSA-N

Description

Application

Structure-activity relationship for tetramisole derivatives as alkaline phosphatase inhibitors.

Suitable for inhibition of various mammalian alkaline phosphatases (i.e., liver, kidney, placenta, bone and tumor). Intestinal alkaline phosphatases are only slightly inhibited.

Other Notes

Racemic form of levamisole.

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pictograms

GHS07

signalword

Warning

hcodes

H302,H315,H319,H335

pcodes

P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c