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Merck
CN

T2006

L-Tyrosine hydrochloride

≥98% (TLC)

Synonym(s):

3-(4-Hydroxyphenyl)-L-alanine, 3-(4-Hydroxyphenyl)-L-alanine hydrochloride

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About This Item

Linear Formula:
HOC6H4CH2CH(NH2)CO2H·HCl
CAS Number:
Molecular Weight:
217.65
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.32
MDL number:
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Product Name

L-Tyrosine hydrochloride, ≥98% (TLC)

biological source

synthetic (organic)

Quality Level

assay

≥98% (TLC)

form

powder

color

white to off-white

mp

239 °C (dec.) (lit.)

SMILES string

Cl[H].N[C@@H](Cc1ccc(O)cc1)C(O)=O

InChI

1S/C9H11NO3.ClH/c10-8(9(12)13)5-6-1-3-7(11)4-2-6;/h1-4,8,11H,5,10H2,(H,12,13);1H/t8-;/m0./s1

InChI key

JJWFIVDAMOFNPS-QRPNPIFTSA-N

Gene Information

human ... GRIN2C(2905)
mouse ... GRIN2C(14813)
rat ... GRIN2C(24411)

Biochem/physiol Actions

Tyrosine is a nonessential amino acid found in mammal, fish and birds. It participates in protein modification, such as phosphorylation, nitrosation and sulfation. It is involved in immune response regulation and prevents the generation of inflammatory cytokines and superoxide. Tyrosine serves as a precursor for epinephrine, norepinephrine, dopamine, thyroid hormones and melanin biosynthesis. Tyrosine phosphorylation is associated with a number of cellular processes such as cell proliferation and migration, development of the embryo, cellular metabolism and transcription. Tyrosine phosphorylation also aids activation of the enzymatic function of a protein.

Other Notes

Amino acid precursor of dopamine and other catecholamines


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Resistance to Tyrosine Kinase Inhibitors, 37(1), 30-30 (2016)
Amino acids: metabolism, functions, and nutrition.
Wu G
Amino Acids, 37(1), 1-17 (2009)



Global Trade Item Number

SKUGTIN
T2006-1G04061826214565
T2006-10G04061832726953
T2006-5G04061832726960