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T2320

T0901317

≥98%

Synonym(s):

N-(2,2,2-Trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide

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About This Item

Empirical Formula (Hill Notation):
C17H12NSO3F9
CAS Number:
293754-55-9
Molecular Weight:
481.33
NACRES:
NA.25
PubChem Substance ID:
24900032
UNSPSC Code:
12352106
MDL number:
MFCD03412028
Assay:
≥98%
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Quality Segment

assay

≥98%

mol wt

481.3

storage temp.

−20°C

SMILES string

OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c2ccccc2)(C(F)(F)F)C(F)(F)F

InChI

1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2

InChI key

SGIWFELWJPNFDH-UHFFFAOYSA-N

Gene Information

Application

T0901317 has been used in LXR agonist study in order to observe the expression of all dietary cholesterol-regulated genes in mice. It has also been used to stimulate the radiolabeled peritoneal macrophages from WT (wildtype) and Tg (transgenic) mice for cellular cholesterol efflux assay.

Biochem/physiol Actions

T0901317 can prevent the secretion of insulin by acting on the metabolism of mitochondria.
LXR agonist whose treatment results in an LXR-dependent up-regulation of ABC1 gene expression

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Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

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