T2896
Triflupromazine hydrochloride
Synonym(s):
N,N-Dimethyl-2-(trifluoromethyl)-10H-phenothiazine-10-propanamine monohydrochloride
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About This Item
Empirical Formula (Hill Notation):
C18H19F3N2S · HCl
CAS Number:
Molecular Weight:
388.88
EC Number:
214-149-6
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
3801519
MDL number:
SMILES string
Cl.CN(C)CCCN1c2ccccc2Sc3ccc(cc13)C(F)(F)F
InChI
1S/C18H19F3N2S.ClH/c1-22(2)10-5-11-23-14-6-3-4-7-16(14)24-17-9-8-13(12-15(17)23)18(19,20)21;/h3-4,6-9,12H,5,10-11H2,1-2H3;1H
InChI key
FTNWXGFYRHWUKG-UHFFFAOYSA-N
Gene Information
human ... DRD2(1813)
Application
Triflupromazine hydrochloride has been used for the screening of inhibitors of S. mansoni miracidial transformation5. It has also been used to study its intracellular localization in central nervous system cells using secondary ion mass spectrometry microscopy6.
Biochem/physiol Actions
Triflupromazine is a D2 dopamine antagonist and a phenothiazine antipsychotic. It is also a potent tranquilizer7 and can significantly reduce body temperature8.
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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