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T3068

Thrombin generation chromogenic substrate

≥90% (HPLC), solid

Synonym(s):

β-Ala-Gly-Arg-p-nitroanilide diacetate

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About This Item

Empirical Formula (Hill Notation):
C21H34N8O9
Molecular Weight:
542.54
UNSPSC Code:
12352204
NACRES:
NA.32
MDL number:
MFCD03453625
Form:
solid
Assay:
≥90% (HPLC)
Biological source:
synthetic (organic)
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biological source

synthetic (organic)

Quality Segment

200

assay

≥90% (HPLC)

form

solid

technique(s)

activity assay: suitable

storage temp.

2-8°C

SMILES string

[N+](=O)([O-])c1ccc(cc1)NC(=O)[C@@H](NC(=O)CNC(=O)CCN)CCCNC(=N)N.OC(=O)C.OC(=O)C

InChI key

PBMJNSQKWBTVOL-GXKRWWSZSA-N

Application

Thrombin generation chromogenic substrate can be used for chromogenic assay developed through aptamer affinity capture and a subsequent enzyme reaction for detecting the thrombin in dilute human serum.

Biochem/physiol Actions

Thrombin generation chromogenic substrate also known as beta-Ala-Gly-Arg para-nitroanilide, is proteolytically cleaved by human thrombin and produces beta-Ala-Gly-Arg and p-nitroanilide. The release of p-nitroanilide is quatified for assesing the anti-thrombin activity.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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