T3577
Tolperisone hydrochloride
≥98% (HPLC), ion channel blocker , solid
Synonym(s):
Menopatol, 2-Methyl-1-(4-methylphenyl)-3-(1-piperidyl)propan-1-one hydrochloride
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About This Item
Empirical Formula (Hill Notation):
C16H23NO · HCl
CAS Number:
Molecular Weight:
281.82
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
222-876-5
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Storage condition:
desiccated
Product Name
Tolperisone hydrochloride, ≥98% (HPLC), solid
Quality Segment
assay
≥98% (HPLC)
form
solid
storage condition
desiccated
color
white
solubility
H2O: >20 mg/mL
storage temp.
room temp
SMILES string
Cl.CC(CN1CCCCC1)C(=O)c2ccc(C)cc2
InChI
1S/C16H23NO.ClH/c1-13-6-8-15(9-7-13)16(18)14(2)12-17-10-4-3-5-11-17;/h6-9,14H,3-5,10-12H2,1-2H3;1H
InChI key
ZBUVYROEHQQAKL-UHFFFAOYSA-N
Biochem/physiol Actions
Tolperisone is derived from piperidine and possesses membrane stabilizing action. It helps in reducing the effect of spasticities associated with the nervous and muscular system. It exhibits muscle relaxant action through attenuating voltage-gated sodium channels in the brain stem.
Tolperisone is an ion channel blocker and centrally acting muscle relaxant.
Tolperisone regulates ionic currents in myelinates axons and subsequently decreases excitability and mediates its antispastic functions3.
Preparation Note
Tolperisone hydrochloride dissolves in water at a concentration that is greater than 20 mg/ml.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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