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Merck
CN

T4897

Thrombin from rabbit plasma

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About This Item

CAS Number:
9002-04-4
UNSPSC Code:
12352202
EC Number:
232-648-7
NACRES:
NA.61
MDL number:
MFCD03792641

Key Documents

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biological source

rabbit plasma

form

solid

specific activity

≥500 units/mg protein

UniProt accession no.

Q28731

shipped in

dry ice

storage temp.

−70°C

Quality Level

200

Gene Information

rabbit ... F2(100009146)

Analysis Note

The NIH assay procedure uses 0.2 ml diluted plasma (1:1 with saline) as a substrate and 0.1 ml of thrombin sample (stabilized in a 1% buffered albumin solution) based on a modification of the method of Biggs. Only clotting times in the range of 15-25 seconds are used for determining thrombin concentrations.

Other Notes

Activity is expressed in NIH units obtained by direct comparison to a NIH Thrombin Reference Standard.
View more information on thrombin at www.sigma-aldrich.com/enzymeexplorer.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

低风险生物材料
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Certificates of Analysis (COA)

Lot/Batch Number
SLCN3409
SLCJ7758
SLBK7723V
017K1094
042K1687

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Articles

Thrombin Factor IIa

Thrombin Factor IIa is an endolytic serine protease that selectively cleaves the Arg--Gly bonds of fibrinogen to form fibrin and release fibrinopeptides A and B.

凝血酶因子IIa

凝血酶因子IIa是一种内切丝氨酸蛋白酶，可选择性地裂解纤维蛋白原的Arg -Gly键，形成纤维蛋白并释放纤维蛋白肽A和B。

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