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Merck
CN

T5771

Testosterone 3-(O-carboxymethyl)oxime: BSA - fluorescein isothiocyanate conjugate

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About This Item

UNSPSC Code:
51111800
NACRES:
NA.77
MDL number:
Assay:
≥98.00% (TLC)
Form:
powder
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assay

≥98.00% (TLC)

Quality Segment

form

powder

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

extent of labeling

~3 mol FITC per mol BSA, ~10 mol steroid per mol BSA

technique(s)

flow cytometry: suitable

solubility

water: 1.90-2.10 mg/mL, clear to faintly hazy, orange

shipped in

ambient

storage temp.

2-8°C

Application

Testosterone 3-(O-carboxymethyl)oxime: BSA-FITC has been used for flow cytometric assays in serum-free cell cultures2. It has also been used for fluorescence labeling experiments in L6 cells3.

Biochem/physiol Actions

Studies have reported that BSA-coupled testosterone can block the growth of LNCaP cells. Furthermore, it can activate Fas protein and cell death, as well as reduce the translocation, adhesion and incursion of iAR-negative, DU145 prostate cancer cells2.


pictograms

Health hazardExclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges



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