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T6443

Tyrphostin AG 370

≥98%

Synonym(s):

2-Amino-4-(1H-indo-5′-yl)-1,1,3-tricyanobuta-1,3-diene, Tyrphostin B7

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About This Item

Empirical Formula (Hill Notation):
C15H9N5
CAS Number:
134036-53-6
Molecular Weight:
259.27
UNSPSC Code:
12352200
PubChem Substance ID:
329826844
MDL number:
MFCD00236449
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assay

≥98%

form

solid

mp

289 °C

solubility

DMSO: soluble

storage temp.

−20°C

SMILES string

NC(\C(=C/c1ccc2[nH]ccc2c1)C#N)=C(\C#N)C#N

InChI

1S/C15H9N5/c16-7-12(15(19)13(8-17)9-18)6-10-1-2-14-11(5-10)3-4-20-14/h1-6,20H,19H2/b12-6-

InChI key

CMMDWEJTQUTCKG-SDQBBNPISA-N

Application

Tyrphostin AG 370 has been used for inhibiting platelet-derived growth factor (PDGF) signaling in human mesenchymal stem cells1,2.

Biochem/physiol Actions

Inhibitor of PDGF-induced cell proliferation.

Preparation Note

Tyrphostin AG 370 is soluble in DMSO.

Disclaimer

Photosensitive

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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