All Photos(5)

Documents

T8441

L-Threonine

Name: <SC>L</SC>-Threonine
Brand: SIGMA

from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 99.0-101.0%

Sign Into View Organizational & Contract Pricing

All Photos(5)

Synonym(s):

(2S,3R)-2-Amino-3-hydroxybutyric acid

Linear Formula:

CH₃CH(OH)CH(NH₂)CO₂H

CAS Number:

72-19-5

Molecular Weight:

119.12

Beilstein:

1721646

EC Number:

200-774-1

MDL number:

MFCD00064270

eCl@ss:

32160406

PubChem Substance ID:

24900531

NACRES:

NA.26

biological source

non-animal source

Quality Level

300

Agency

USP/NF
meets EP testing specifications
meets JP testing specifications
meets USP testing specifications

product line

BioXtra

Assay

99.0-101.0%

form

powder

quality

meets EP, JP, USP testing specifications

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

white

mp

256 °C (dec.) (lit.)

solubility

H₂O: 1 g/10 mL, clear, colorless

application(s)

pharmaceutical (small molecule)

SMILES string

C[C@@H](O)[C@H](N)C(O)=O

InChI

1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3+/m1/s1

InChI key

AYFVYJQAPQTCCC-GBXIJSLDSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Amino Acids

Exclusive Savings

High-Purity Biochemicals and Reagents

General description

L-Threonine is a naturally occurring amino acid belonging to the aspartate family of amino acids.

Application

L-Threonine has been used for the following :

To study the effect of heat on homoserine kinase activity
In Plackett–Burman analysis and then to study the effect of selected amino acids on monoclonal antibody production in CHO cells
As a substrate to determine the L-threonine dehydrogenase activity
To study the effect of L-Threonine on the growth rate of P. putida, to check for its tolerance towards L-Threonine

Biochem/physiol Actions

L-Threonine is considered to be an essential amino acid. L-Threonine is involved in the synthesis of mucin, a protein supporting intestinal function and integrity. L-Threonine is required for the performance of the immune system. It is also essential for O-linked glycosylation, protein phosphorylation and glycine synthesis.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

How to Find the Product Number

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503

Product Number

25G

Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

How to Find a Lot/Batch Number for COA

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').
For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').
For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Homoserine Kinase from Escherichia coli K-12: Properties,
Inhibition by L-Threonine, and Regulation of Biosynthesis

J. THEZE

Journal of Bacteriology, 118(2), 577-581 (1974)

Use of a Plackett-Burman statistical design to determine the effect of selected amino acids on monoclonal antibody production in CHO cells.

Gonzalez-Leal IJ

Biotechnol. Progress, 27(6), 1709-1717 (2011)

Genome-wide identification of tolerance mechanisms toward p-coumaric acid in Pseudomonas putida

Patricia Calero

Biotechnology and Bioengineering, 115(3), 762-774 (2018)

Systems metabolic engineering of Escherichia coli for L?threonine production.

Lee HK, et al.

Molecular Systems Biology, 3(1), 149-149 (2007)

Regulation of L-Threonine Dehydrogenase in Somatic Cell Reprogramming

Chuanchun Han

Stem Cells, 31(5) (2013)

View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service