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Merck
CN

T8532

Triton™ X-100

suitable for electrophoresis

Synonym(s):

t-Octylphenoxypolyethoxyethanol, Polyethylene glycol tert-octylphenyl ether

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About This Item

Linear Formula:
t-Oct-C6H4-(OCH2CH2)xOH, x= 9-10
CAS Number:
9036-19-5
PubChem Substance ID:
329826882
UNSPSC Code:
12161900
Beilstein/REAXYS Number:
2315025
MDL number:
MFCD00128254

Key Documents

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SMILES string

CC(C)(C)CC(C)(C)c1ccc(OCCOCCOCCOCCOCCOCCOCCO)cc1

InChI

1S/C28H50O8/c1-27(2,3)24-28(4,5)25-6-8-26(9-7-25)36-23-22-35-21-20-34-19-18-33-17-16-32-15-14-31-13-12-30-11-10-29/h6-9,29H,10-24H2,1-5H3

InChI key

HNLXNOZHXNSSPN-UHFFFAOYSA-N

description

non-ionic

form

liquid

mol wt

micellar avg mol wt 80,000, average mol wt 625

technique(s)

DNA extraction: suitable, DNA purification: suitable, electrophoresis: suitable

color

APHA: ≤100

turbidity

≤5.0 NTU

CMC

0.2-0.9 mM (20-25°C)

transition temp

pour point ~7 °C

solubility

water: soluble

density

1.06 g/mL at 25 °C (lit.)

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Application

Detergent used for isoelectric focusing (IEF) and two-dimensional electrophoresis. Concentrations between 1-4% (v/v) are typically used in an IEF gel. Also used for cell permeabilization and protein solubilization including high molecular mass proteins.

Biochem/physiol Actions

Widely used non-ionic surfactant for recovery of membrane components under mild non-denaturing conditions.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Legal Information

Triton is a trademark of The Dow Chemical Company or an affiliated company of Dow

signalword

Danger

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

483.8 °F - closed cup

flash_point_c

251 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - ED ENV 1 - Eye Dam. 1 - Skin Irrit. 2

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
0000369569
0000369569
SLCB9975
SLBW9891
MKBH4307V

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Allison E Songstad et al.
Stem cells translational medicine, 6(6), 1533-1546 (2017-05-06)
Age-related macular degeneration (AMD) is a leading cause of irreversible blindness in the Western world. Although, the majority of stem cell research to date has focused on production of retinal pigment epithelial (RPE) and photoreceptor cells for the purpose of
Leonard Herrfurth et al.
Frontiers in molecular neuroscience, 10, 2-2 (2017-02-15)
Vascular endothelial growth factor (VEGF) is well known as the growth factor with wide-ranging functions even in the central nervous system (CNS). Presently, most attention is given to the investigation of its role in neuronal protection, growth and maturation processes
Friederike Pfeiffer et al.
Acta neuropathologica, 122(5), 601-614 (2011-10-11)
In experimental autoimmune encephalomyelitis (EAE), an animal model for multiple sclerosis (MS), loss of the blood-brain barrier (BBB) tight junction (TJ) protein claudin-3 correlates with immune cell infiltration into the CNS and BBB leakiness. Here we show that sealing BBB
Adam A Strömstedt et al.
Antimicrobial agents and chemotherapy, 53(2), 593-602 (2008-11-26)
Methods for increasing the proteolytic stability of EFK17 (EFKRIVQRIKDFLRNLV), a new peptide sequence with antimicrobial properties derived from LL-37, were evaluated. EFK17 was modified by four d-enantiomer or tryptophan (W) substitutions at known protease cleavage sites as well as by
Manuela Rinaldi et al.
Veterinary research, 42, 61-61 (2011-05-17)
The mucus layer in the gastrointestinal (GI) tract is considered to be the first line of defense to the external environment. Alteration in mucus components has been reported to occur during intestinal nematode infection in ruminants, but the role of
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Product Information Sheet - T8532

Product Information Sheet

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