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Merck
CN

T9753

D-Tryptophan

≥98.0% (HPLC)

Synonym(s):

(R)-2-Amino-3-(3-indolyl)propionic acid, D-α-Amino-3-indolepropionic acid

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About This Item

Empirical Formula (Hill Notation):
C11H12N2O2
CAS Number:
153-94-6
Molecular Weight:
204.23
NACRES:
NA.32
PubChem Substance ID:
24900598
UNSPSC Code:
12352103
EC Number:
205-819-9
MDL number:
MFCD00005647
Beilstein/REAXYS Number:
86198

Key Documents

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Product Name

D-Tryptophan, ≥98.0% (HPLC)

InChI key

QIVBCDIJIAJPQS-SECBINFHSA-N

InChI

1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m1/s1

SMILES string

N[C@H](Cc1c[nH]c2ccccc12)C(O)=O

biological source

synthetic (organic)

assay

≥98.0% (HPLC)

form

powder

technique(s)

cell culture | embryo: suitable
cell culture | mammalian: suitable

color

white to off-white

mp

282-285 °C (dec.) (lit.)

Quality Level

200

Gene Information

human ... GRINA(2907)
mouse ... GRINA(66168)
rat ... GRINA(266668)

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Application

D-Tryptophan has been used to study its efficacy on dispersing biofilm in dental unit waterlines (DUWLs) in vitro.
D-Tryptophan can be used for Human embryonic kidney cell (HEK-293, ATCC: CRL-1573) culture.The product is a sweetener used to study the release of incretins from enteroendocrine cells triggered by sugar but not by sweeteners.

Biochem/physiol Actions

Low level of D-tryptophan is capable of preventing the growth of an L-tryptophan-requiring mutant of the E. coli.

General description

Tryptophan is one of the essential and standard amino acids present in the body. It is used by the cells to produce proteins.

Other Notes

Unnatural isomer of tryptophan.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
MKCW0243
MKCT7977
MKCT0095
MKCS3587
MKCR3947

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Yu Sakurai et al.
Molecular pharmaceutics, 17(4), 1397-1404 (2020-02-25)
Peptide modification is a popular strategy for developing an active targeting lipid nanoparticle (LNP). In modifying the surface of an LNP with a peptide, the sequence and structure of the peptide strongly affects the formation of the LNP. Specifically, a
Action of D-Tryptophan on E. coli
Hatanaka M
Nature, 204(4954), 202-203 (1964)
Fangjie Zheng et al.
Electrophoresis, 40(16-17), 2218-2226 (2019-04-27)
Establishing a simple and accurate method for Hg2+ detection is of great importance for the environment and human health. In this work, platinum nanoparticles (Pt NPs) with different capped agents and morphologies were synthesized. It was found that Pt NPs
Shi Xuan Leong et al.
ACS nano, 15(1), 1817-1825 (2021-01-06)
Chiral differentiation is critical in diverse fields ranging from pharmaceutics to chiral synthesis. While surface-enhanced Raman scattering (SERS) offers molecule-specific vibrational information with high detection sensitivity, current strategies rely on indirect detection using additional selectors and cannot exploit SERS' key
Application of D-Amino Acids as Biofilm Dispersing Agent in Dental Unit Waterlines
Ampornaramveth RS, et al.
International journal of dentistry, 2018(4954) (2018)
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