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U0631

Urea

Name: Urea
Brand: SIGMA

BioXtra, pH 7.5-9.5 (20 °C, 5 M in H₂O)

Synonym(s):

Carbamide, Carbonyldiamide

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About This Item

Linear Formula:

NH₂CONH₂

CAS Number:

57-13-6

Molecular Weight:

60.06

UNSPSC Code:

12352111

NACRES:

NA.31

PubChem Substance ID:

24900617

EC Number:

200-315-5

Beilstein/REAXYS Number:

635724

MDL number:

MFCD00008022

Assay:

98.5-101.5%

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product line

BioXtra

Quality Level

200

assay

98.5-101.5%

form

powder, crystals or pellets

impurities

≤0.005% Phosphorus (P), ≤0.1% Insoluble matter

ign. residue

≤0.1%

pH

7.5-9.5 (20 °C, 5 M in H₂O)

mp

132-135 °C (lit.)

solubility

H₂O: 5 M at 20 °C, clear, colorless

density

1.335 g/mL at 25 °C (lit.)

anion traces

chloride (Cl^-): ≤0.05%, sulfate (SO₄^2-): ≤0.05%

cation traces

Al: ≤0.0005%, Ca: ≤0.001%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Mg: ≤0.0005%, NH₄⁺: ≤0.05%, Na: ≤0.005%, Pb: ≤0.001%, Zn: ≤0.0005%

absorption

≤0.06 at 260 nm at 5 M, ≤0.06 at 280 nm at 5 M

application(s)

diagnostic assay manufacturing

SMILES string

NC(N)=O

InChI

1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)

InChI key

XSQUKJJJFZCRTK-UHFFFAOYSA-N

Gene Information

human ... CA1(759), CA2(760)
rat ... Ppm1a(24666)

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Related Categories

Biochemicals

High-Purity Biochemicals and Reagents

Application

Used for the denaturation of proteins and as a mild solubilization agent for insoluble or denatured proteins. Useful for renaturing proteins from samples already denatured with 6 M guanidine chloride such as inclusion bodies. May be used with guanidine hydrochloride and dithiothreitrol (DTT) in the refolding of denatured proteins into their native or active form.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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A unique role for p53 in the regulation of M2 macrophage polarization.

L Li et al.

Cell death and differentiation, 22(7), 1081-1093 (2014-12-20)

P53 is critically important in preventing oncogenesis but its role in inflammation in general and in the function of inflammatory macrophages in particular is not clear. Here, we show that bone marrow-derived macrophages exhibit endogenous p53 activity, which is increased

A mechanically and electrically self-healing supercapacitor.

Hua Wang et al.

Advanced materials (Deerfield Beach, Fla.), 26(22), 3638-3643 (2014-02-21)

Proteome adaptation in cell reprogramming proceeds via distinct transcriptional networks.

Marco Benevento et al.

Nature communications, 5, 5613-5613 (2014-12-11)

The ectopic expression of Oct4, Klf4, c-Myc and Sox2 (OKMS) transcription factors allows reprogramming of somatic cells into induced pluripotent stem cells (iPSCs). The reprogramming process, which involves a complex network of molecular events, is not yet fully characterized. Here

Stereoselective metal-free synthesis of β-amino thioesters with tertiary and quaternary stereogenic centers.

Annette Bahlinger et al.

Angewandte Chemie (International ed. in English), 53(33), 8779-8783 (2014-03-20)

β-Amino thioesters are important natural building blocks for the synthesis of numerous bioactive molecules. An organocatalyzed Mannich reaction was developed which provides direct and highly stereoselective access to acyclic β(2)- and β(2,3,3)-amino thioesters with adjacent tertiary and quaternary stereocenters. Mechanistic

Metabolites of the kynurenine pathway of tryptophan metabolism in the cerebrospinal fluid of Malawian children with malaria.

Isabelle M Medana et al.

The Journal of infectious diseases, 188(6), 844-849 (2003-09-10)

A retrospective study of 100 Malawian children (87 with malaria and 13 with a diagnosis other than malaria) was conducted to determine the relationship between levels of metabolites of the kynurenine pathway in cerebrospinal fluid (CSF) and disease outcome. Three

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Global Trade Item Number

SKU	GTIN
U0631-5KG	04061837403798
U0631-1KG	04061837403774
U0631-500G	04061837403781

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