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U211100

DMT-2′O-Methyl-rU Phosphoramidite

Name: DMT-2′O-Methyl-rU Phosphoramidite
Brand: SIGMA

Synonym(s):

5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-methyl-uridine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite], DMT-2′O-Methyl-rU amidite

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About This Item

Empirical Formula (Hill Notation):

C₄₀H₄₉N₄O₉P

CAS Number:

110764-79-9

Molecular Weight:

760.81

NACRES:

NA.51

PubChem Substance ID:

329827605

UNSPSC Code:

41116105

MDL number:

MFCD00792626

Assay:

≥99% (³¹P-NMR), ≥99.0% (reversed phase HPLC)

Biological source:

non-animal source (no BSE/TSE risk)

Form:

powder

Storage temp.:

-10 to -25°C

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biological source

non-animal source (no BSE/TSE risk)

Quality Level

300

assay

≥99% (³¹P-NMR), ≥99.0% (reversed phase HPLC)

form

powder

impurities

≤0.1% single unspecified Impurity (reversed phase HPLC), ≤0.3% mU2 (reversed phase HPLC, Hydrolysate), ≤0.3% mU3 (reversed phase HPLC, DMT-rme), ≤0.3 wt. % water content (Karl Fischer), ≤0.5% P(III) Impurities 100-169ppm (³¹P-NMR), ≤1.0% mU1 (reversed phase HPLC, DMT-rUme-DMT), ≤3 wt. % residual Solvent content

color

white to off-white

λ

conforms (UV/VIS Identity)

suitability

conforms to structure for H-NMR, conforms to structure for LC-MS

nucleoside profile

base: uridine
base protecting group: none
2' protecting group: methyl
5' protecting group: DMT
deprotection: fast/standard

storage temp.

-10 to -25°C

SMILES string

CO[C@@H]1[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H](COC(c2ccccc2)(c3ccc(OC)cc3)c4ccc(OC)cc4)O[C@H]1N5C=CC(=O)NC5=O

InChI

1S/C40H49N4O9P/c1-27(2)44(28(3)4)54(51-25-11-23-41)53-36-34(52-38(37(36)49-7)43-24-22-35(45)42-39(43)46)26-50-40(29-12-9-8-10-13-29,30-14-18-32(47-5)19-15-30)31-16-20-33(48-6)21-17-31/h8-10,12-22,24,27-28,34,36-38H,11,25-26H2,1-7H3,(H,42,45,46)/t34-,36-,37-,38-,54?/m1/s1

InChI key

UVUOJOLPNDCIHL-XKZJCBTISA-N

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

No data available

flash_point_c

No data available

Regulatory Information

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Global Trade Item Number

SKU	GTIN
U211100-AGL	04061826593431
U211100-500G	04061832026336
U211100-BIO	04061826572399
U211100-AVC	04061826572382
U211100-100G	04061832026329
U211100-C	04061826593448

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