U211100
DMT-2′O-Methyl-rU Phosphoramidite
Synonym(s):
5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-methyl-uridine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite], DMT-2′O-Methyl-rU amidite
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About This Item
biological source
non-animal source (no BSE/TSE risk)
Quality Segment
assay
≥99% (31P-NMR), ≥99.0% (reversed phase HPLC)
form
powder
impurities
≤0.1% single unspecified Impurity (reversed phase HPLC), ≤0.3% mU2 (reversed phase HPLC, Hydrolysate), ≤0.3% mU3 (reversed phase HPLC, DMT-rme), ≤0.3 wt. % water content (Karl Fischer), ≤0.5% P(III) Impurities 100-169ppm (31P-NMR), ≤1.0% mU1 (reversed phase HPLC, DMT-rUme-DMT), ≤3 wt. % residual Solvent content
color
white to off-white
λ
conforms (UV/VIS Identity)
suitability
conforms to structure for H-NMR, conforms to structure for LC-MS
nucleoside profile
base: uridine
base protecting group: none
2' protecting group: methyl
5' protecting group: DMT
deprotection: fast/standard
storage temp.
-10 to -25°C
SMILES string
CO[C@@H]1[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H](COC(c2ccccc2)(c3ccc(OC)cc3)c4ccc(OC)cc4)O[C@H]1N5C=CC(=O)NC5=O
InChI
1S/C40H49N4O9P/c1-27(2)44(28(3)4)54(51-25-11-23-41)53-36-34(52-38(37(36)49-7)43-24-22-35(45)42-39(43)46)26-50-40(29-12-9-8-10-13-29,30-14-18-32(47-5)19-15-30)31-16-20-33(48-6)21-17-31/h8-10,12-22,24,27-28,34,36-38H,11,25-26H2,1-7H3,(H,42,45,46)/t34-,36-,37-,38-,54?/m1/s1
InChI key
UVUOJOLPNDCIHL-XKZJCBTISA-N
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
No data available
flash_point_c
No data available
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